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新兴的策略对分子降解剂的潜在发现

Baiyun Wang1, Shiyun Cao1, Ning Zheng1

  • 1Department of Pharmacology, Box 357280, University of Washington, Seattle, WA, USA; Howard Hughes Medical Institute, University of Washington, Seattle, WA, USA.

Current opinion in structural biology
|April 10, 2024
PubMed
概括

分子粘剂 (MGs) 是一种新型降解剂,利用E3酶进行向蛋白质分解. 通过利用弱相互作用,MGs为开发针对疾病点的新疗法提供了有前途的战略.

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