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Updated: Jun 28, 2025

Adoptive Transfer of IL-33-Stimulated Macrophages into Bleomycin-Induced Mouse Models to Study Their Effect on Idiopathic Pulmonary Fibrosis In Vivo
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生物质燃料相关的PM2.5通过PI3K/AKT/TRPC1路径促进肺纤维细胞-肌纤维细胞过渡

Shuni Li1, Lihui Qu1, Lifen Zhou1

  • 1State Key Laboratory of Respiratory disease, Department of Physiology, School of Basic Medical Sciences, Guangzhou Medical University, Guangzhou, Guangdong, RP China.

Ecotoxicology and environmental safety
|April 10, 2024
PubMed
概括

生物质燃料相关的细颗粒物 (BRPM2.5) 暴露会导致气道炎症和重塑,导致慢性阻塞性肺病 (COPD). PI3K/AKT/TRPC1通路调解了这一过程,为纤维化提供了潜在的治疗点.

关键词:
生物质燃料相关的PM{2.5)纤维细胞细胞.肌纤维细胞细胞.在PI3K/AKT中使用.TRPC1 是一个人.

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