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Updated: Jun 28, 2025

Live Imaging Assay for Assessing the Roles of Ca2+ and Sphingomyelinase in the Repair of Pore-forming Toxin Wounds
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有关ROS的S-palmitoylation激活物分离和完整的Gasdermin D

Gang Du1,2, Liam B Healy3,4, Liron David5,6,7

  • 1Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, USA. gdu@crystal.harvard.edu.

Nature
|April 10, 2024
PubMed
概括

气体皮质D (GSDMD) 是棕化,这是一种在热过程中对孔隙形成至关重要的改变. 这种可逆的棕化作为GSDMD激活的关键开关,挑战了先前的分裂是唯一的触发因素.

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