用灵活的冷探针对猪进行图像引导的横支气管肺冷处理:性能和放射学-病理学相关性
Quirina M B de Ruiter1, Michal M Mauda-Havakuk2, Matthew F Starost3
1Center for Interventional Oncology, Radiology & Imaging Sciences, Clinical Center, National Institutes of Health, Bethesda, Maryland.
Journal of vascular and interventional radiology : JVIR
|April 10, 2024
概括
灵活的横支气管冷探测器显示了肺切除的可行性,在形光束CT上可见的冷损伤. 这种新方法提供了类似的病理 transthoracic cryoablation.
科学领域:
- 肺部医学 肺部医学
- 干预性放射学 干预性放射学
- 手术技术 手术技术
背景情况:
- 结冷处理是一种有效的微创治疗肺病变.
- 目前的冷化技术通常涉及刚性探头和穿皮方法.
- 灵活的探针提供了不那么侵袭的潜力,内支气管输送.
研究的目的:
- 为了评估一种新的灵活的横支气管冷探针的性能.
- 为了比较其对皮肤穿越胸部冷的疗效.
- 通过使用圆光束CT来描述化成像和病理特征.
主要方法:
- 一种灵活的冷探针原型被用于猪模型的横支气管肺切除.
- 用刚性探针进行的横胸部冷处理作为比较器.
- 形光束CT用于手术内成像,与毛细和组织病理学相关联.
主要成果:
- 灵活的冷探头在所有跨支气管手术中成功导航和部署.
- 化被可视化在形光束CT上,其体积与横胸切除相当.
- 图像学与总体和组织病理学有很好的相关性,尽管发生了一次肺胸病.
结论:
- 使用灵活的冷探针进行横支气管冷处理是一种可行的技术.
- 通过这种方法创建的结晶可以用形光束CT检测到.
- 跨支气管冷凝的病理学反映了跨胸部冷凝的病理学.
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