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来自燃烧源的PM_2.5中的空气中环境持久性自由基 (EPFR):丰富性,细胞毒性和潜在暴露风险

Zhen Zhao¹, Hanhan Li², Yaqian Wei²

¹International Center for Ecology, Meteorology, and Environment, School of Ecology and Applied Meteorology, Nanjing University of Information Science & Technology, Nanjing 210044, China; Zhejiang Academy of Agricultural Sciences, Hangzhou 310021, China; Multiphase Chemistry Department, Max Planck Institute for Chemistry, 55128 Mainz, Germany.

The Science of the total environment

|April 10, 2024

概括

来自燃烧源的微粒颗粒物 (PM2.5) 中的空气中环境持久的自由基 (EPFR) 构成健康风险. 含有EPFR的汽车废气PM2.5显著增加了活性氧物种 (ROS),突出了依赖来源的健康影响.

科学领域:

环境科学环境科学
大气化学大气化学
毒理学毒理学毒理学

背景情况:

空气中的环境持久性自由基 (EPFR) 是燃烧产生的新兴大气污染物.
来自各种来源的细颗粒物 (PM2.5) 与有害健康影响有关.
评估来自不同排放源的PM2.5对健康的影响对于控制空气污染至关重要.

研究的目的:

为了确定煤炭燃烧,生物质燃烧和汽车排气中的PM2.5中的EPFR度.
评估EPFRs在PM2.5.5中的体外细胞毒性和氧化潜力.
提供PM2.5.5中EPFRs对健康的来源和度相关影响的证据.

主要方法:

从煤炭燃烧,生物质燃烧和汽车废气中采集PM2.5样本,使用部分流量稀释道.
在收集的PM2.5样本中量化EPFR度.
进行了体外细胞毒性和氧化潜力测定.

主要成果:

从所有三种排放来源的PM2.5中发现了EPFR的大量度.
与PM2.5相关的EPFR显示出显著的潜在暴露风险.
在PM2.5中的EPFRs,特别是来自汽车废气,诱导了实质性的活性氧物种 (ROS) 在体外生成.

结论:

PM2.5中的EPFRs有助于对健康产生不利影响,汽车排气是其中一个重要来源.
在PM2.5中EPFR的健康影响取决于排放源和度.
需要进一步的研究,以推进以公共卫生为导向的PM2.5排放控制战略.

关键词:

燃烧的来源燃烧的来源细胞毒性细胞毒性这些EPFR是EPFR.危害健康的健康风险在 ROS 生产过程中,

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