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Updated: Jun 28, 2025

Using Caco-2 Cells to Study Lipid Transport by the Intestine
07:00

Using Caco-2 Cells to Study Lipid Transport by the Intestine

Published on: August 20, 2015

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对Caco-2微流体芯片模型的验证,用于预测BCS I-IV类药物的肠道吸收

Stephanie Y Zhang1, Whitney S Y Ong2, Natalia Subelzu2

  • 1Pharmaceutical Sciences and Clinical Supply, Merck & Co., Inc., Rahway, NJ 07065, USA.

International journal of pharmaceutics
|April 10, 2024
PubMed
概括

一个新的微流体肠道芯片显示出预测口服药物吸收的前景,其结果与传统的Caco-2 Transwell测试相似. 这种经过验证的gut-on-a-chip模型减少了对药物开发的动物试验的依赖.

关键词:
生物制药生物制药公司在芯片上的肠道.IVIVC IVIVC IVIVC IVIVC IVIVC IVIVC IVIVC IVIVC IVIVC IVIVC IVIVC IVIVC IVIVC IVIVC IVIVC IVIVC IVIVC IVIVC IVIVC IVIVC微流体学 微流体学透性 透性的

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