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Updated: Jun 28, 2025

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纳米粒子与淋巴系统之间的相互作用:药物输送中的机制和应用

Yisi Tang1, Bao Liu2, Yuting Zhang2

  • 1State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100050, China; Beijing Key Laboratory of Drug Delivery Technology and Novel Formulation, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100050, China; NHC Key Laboratory of Comparative Medicine, National Center of Technology Innovation for Animal Model, Institute of Laboratory Animal Sciences, Chinese Academy of Medical Sciences and Comparative Medicine Center, Peking Union Medical College, Beijing 100021, China.

Advanced drug delivery reviews
|April 10, 2024
PubMed
概括

本综述探讨了淋巴系统用于药物输送,详细介绍了纳米药物如何导航淋巴血管和节点. 它强调了加强药物向和系统暴露的挑战和进展.

关键词:
树突细胞的树突细胞.淋巴结的 淋巴结的 淋巴结的淋巴输送系统是淋巴输送系统.淋巴系统 淋巴系统蛋白质冠状冠状病毒疫苗 疫苗 疫苗 疫苗

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The selection of a drug's delivery route depends upon its physicochemical properties, including lipid or water solubility and ionization, as well as the therapeutic requirement, such as immediate or sustained effect. These routes can be divided into three primary categories: enteral, parenteral, and topical.
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Body tissues, comprising approximately 40% of the body weight, are crucial in drug distribution and localization. These tissues can serve as drug storage sites, competing with plasma binding sites for drug molecules.
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