相关实验视频

Updated: Jun 28, 2025

A Syngeneic Mouse Model of Metastatic Renal Cell Carcinoma for Quantitative and Longitudinal Assessment of Preclinical Therapies

A Syngeneic Mouse Model of Metastatic Renal Cell Carcinoma for Quantitative and Longitudinal Assessment of Preclinical Therapies

Published on: April 12, 2017

[一个与crizotinib相关的囊病例]

L L Quan¹, P Huang¹, Y C Liang¹

¹Department of Pulmonary and Critical Care Medicine, Zhuzhou Central Hospital/the Affiliated Zhuzhou Hospital Xiangya Medical College CSU, Zhuzhou 412007, China.

Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases

|April 10, 2024

概括

与克里佐替尼相关的囊 (CARC) 通常在停止治疗后消失. 然而,罕见的侵袭性CARC病例表明它们侵入了周围组织,这凸显了在crizotinib治疗期间需要保持警的必要性.

科学领域:

在瘤学瘤学.
腎臟病學 (nephrology) 是一種醫學專業.
药理学药理学是指药理学的学科.

背景情况:

克里佐替尼 (crizotinib) 是针对形淋巴瘤激酶 (ALK) 阳性肺癌的向治疗.
与克里佐替尼相关的囊 (CARC) 是已知的副作用,通常是良性的和可逆的.
一些CARC病例表现出具有局部入侵的侵略性行为.

研究的目的:

描述crizotinib相关囊的发生和行为.
报告一个具有广泛本地入侵的侵略性CARC病例.
突出药物停用后CARC自发解决的潜力.

主要方法:

关于CARC的文献审查.
用crizotinib治疗的患有EML4-ALK融合突变的病人的病例报告分析.
在克里佐替尼治疗期间和之后监测和肌肉囊性变化.

主要成果:

大多数CARC在停止使用crizotinib后自发消失.
一个罕见的激进的CARC病例显示脏,大和直肠肌肉的入侵.
报告病例中的囊性变化在停止使用crizotinib后得到解决.

结论:

CARC通常是可逆的,但侵略性形式需要监测.
及时识别和停止使用crizotinib可能会导致侵略性CARC.的解决.
这一案例强调了CARC.的可变表现和潜在的侵入性.

更多相关视频

Identification of the Source of Secreted Proteins in the Kidney by Brefeldin A Injection

Identification of the Source of Secreted Proteins in the Kidney by Brefeldin A Injection

Published on: November 10, 2021

Microscopic Cyst Resection for the Treatment of Patients Diagnosed with Epididymal Cyst

Microscopic Cyst Resection for the Treatment of Patients Diagnosed with Epididymal Cyst

Published on: March 31, 2023

相关概念视频

The Retinoblastoma Gene

The Retinoblastoma Gene

Tumor suppressor genes are normal genes that can slow down cell division, repair DNA mistakes, or program the cells for apoptosis in case of irreparable damage. Hence, they play an essential role in preventing the proliferation of damaged cells.
The first-ever tumor suppressor gene called Rb was identified in retinoblastoma - a rare eye tumor in children. In inherited forms of the disease, a child inherits one defective copy of the Rb gene, which predisposes them to retinoblastoma. However,...