拉丁裔婴儿怀孕前孕产妇肥胖和婴儿神经发育结果
Mahsa Babaei1, Christopher J Machle1,2, Pari Mokhtari1
1Department of Pediatrics, Division of Endocrinology, Diabetes, and Metabolism, Children's Hospital Los Angeles, Los Angeles, California, USA.
Obesity (Silver Spring, Md.)
|April 10, 2024
概括
孕前母亲的BMI会对婴儿的认知和语言发育产生负面影响. 婴儿饮食质量部分介导了这一效应,强调了健康的孕产妇体重和婴儿营养对于更好的神经发育结果的重要性.
科学领域:
- 孕产妇和儿童的健康
- 营养科学 营养科学
- 发育儿科 发育儿科
背景情况:
- 孕前母亲的体重指数 (BMI) 是影响怀孕和分娩结果的关键因素.
- 婴儿神经发育是一个复杂的过程,受到各种遗传和环境因素的影响.
- 低收入的拉丁裔家庭面临着独特的挑战,这些挑战可能会影响母亲和儿童的健康结果.
研究的目的:
- 为了研究母亲怀孕前的BMI和24个月的婴儿神经发育之间的关联.
- 检查婴儿饮食质量在这种关系中的调解作用.
- 为旨在改善弱势群体神经发育结果的干预提供见解.
主要方法:
- 一项对163个低收入拉丁裔母婴夫妇进行纵向研究,对此进行了2年的跟踪.
- 母亲怀孕前的BMI通过自我报告进行评估;婴儿神经发育使用贝利婴儿发育量表在24个月后进行评估.
- 使用健康饮食指数 (HEI)-2015和HEI-Toddlers-2020分数测量婴儿饮食质量;进行中介和回归分析.
主要成果:
- 较高的孕前母亲BMI与24个月的婴儿认知 (β = -0.1,p < 0.001) 和语言分数 (β = -0.1,p = 0.01) 的较低显著相关.
- 24个月的婴儿HEI-2015分数部分调解了这些关联,占对认知和语言分数的影响的23%和30%.
- 没有单个的饮食成分,只有整体HEI-2015得分,调解了这种关系.
结论:
- 管理母亲怀孕前的肥胖是优化婴儿神经发育轨迹的关键.
- 促进健康的孕产妇体重和高质量的婴儿饮食的干预措施对于低收入的拉丁裔家庭至关重要.
- 早期的营养指导和支持可以积极影响婴儿的认知和语言发展.
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