孕产妇的喘和妊娠期间的喘恶化以及后代的注意力缺陷/多动性障碍:基于人口的队列研究
Yi-Feng Ho1,2, Yi-Lung Chen3,4, Robert Stewart5,6
1Institute of Medicine, Chung Shan Medical University, Taichung, Taiwan.
European child & adolescent psychiatry
|April 10, 2024
概括
母亲和父亲的喘增加了儿童注意力缺陷多动症 (ADHD) 的风险. 然而,怀孕期间的喘恶化并没有显示出与后代患ADHD风险的联系.
科学领域:
- 儿科健康 儿科健康
- 遗传学和流行病学
- 神经发育障碍 神经发育障碍
背景情况:
- 人们越来越认识到喘和注意力缺陷多动性障碍 (ADHD) 等炎症状况之间的联系.
- 有限的研究已经探索了与父母喘相关的ADHD风险的代际传播.
研究的目的:
- 调查孕期母性喘,父性喘和母性喘恶化与儿童ADHD风险之间的关联.
- 分析父母喘和后代ADHD发育之间的跨代联系.
主要方法:
- 一项基于人口的队列研究,利用台湾国家健康保险研究数据库 (2004-2017) 的数据.
- 考克斯回归模型被用于评估ADHD风险,并根据各种混因素进行调整.
- 使用兄弟控制方法来解决未测量的混因素对母亲喘恶化.
主要成果:
- 无论是母性喘 (HR: 1.36) 还是父性喘 (HR: 1.10) 都与子女患ADHD的风险增加有显著的关联.
- 与父亲喘相比,母亲喘与后代ADHD风险的相关性更强.
- 怀孕期间急性喘恶化没有发现与后代患ADHD的风险增加有关 (aHR:1.00).
结论:
- 父母喘,无论是母亲还是父亲,都是儿童患ADHD的重要危险因素.
- 这些发现强调了考虑父母健康史的重要性,以了解ADHD病因.
- 根据这项研究,特别是在怀孕期间的喘恶化似乎没有影响后代患ADHD的风险.
更多相关视频
19:15Assessment and Evaluation of the High Risk Neonate: The NICU Network Neurobehavioral Scale
Published on: August 25, 2014
85.9K
06:39Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants
Published on: June 13, 2021
3.1K
相关概念视频
Attention-Deficit/Hyperactivity Disorder
57
Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterized by persistent inattention, hyperactivity, and impulsivity. It affects approximately 5-8% of children globally, with around 60-70% of cases persisting into adulthood. ADHD has significant implications for educational attainment, social interactions, and occupational success.
Diagnostic Criteria and Symptoms
To diagnose ADHD, symptoms must manifest before age 12 and be evident across multiple settings....
Diagnostic Criteria and Symptoms
To diagnose ADHD, symptoms must manifest before age 12 and be evident across multiple settings....
57
Asthma-I: Introduction
2.6K
Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...
2.6K
Upper Respiratory Drugs: Antitussives, Expectorants, and Mucolytics
277
Respiratory symptoms, such as congestion and cough, commonly accompany respiratory tract conditions. Various medications, such as antitussives, expectorants, and mucolytics, play crucial roles in providing relief.
Antitussives include codeine, dextromethorphan (Robitussin), and benzonatate (Tessalon). Codeine and dextromethorphan exert their effects centrally by suppressing the cough reflex center in the medulla. Benzonatate operates peripherally within the respiratory tract by...
Antitussives include codeine, dextromethorphan (Robitussin), and benzonatate (Tessalon). Codeine and dextromethorphan exert their effects centrally by suppressing the cough reflex center in the medulla. Benzonatate operates peripherally within the respiratory tract by...
277
Asthma-II: Pathophysiology and Classification
2.7K
Asthma is a prevalent chronic respiratory condition marked by inflammation and hyperresponsiveness of the airways. Its pathophysiology involves complex interactions among inflammatory pathways, immune responses, and neural mechanisms.
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
2.7K
Asthma: Pathogenesis and Management
391
Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
391
Asthma-IV: Diagnostic and Management
2.5K
The diagnosis and management of asthma are comprehensive, encompassing clinical assessments, lung function tests, and pharmacological interventions. Here's an overview:
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
2.5K
