改善药物处方相关的结果对于高风险药物过渡的弱势老年人 (IMPROVE-IT HRM):一个试点随机试验协议
Anne Holbrook1,2,3, Dan Perri4,5, Mitch Levine4,6
1Division of Clinical Pharmacology and Toxicology, Department of Medicine, McMaster University, Hamilton, ON, Canada. holbrook@mcmaster.ca.
Pilot and feasibility studies
|April 10, 2024
概括
这项研究评估了临床药理和毒理学 (CPT) 药物管理干预措施,用于经常住院治疗的老年人. 该干预旨在减少药物治疗问题和改善护理过渡,其结果可能为更大的国家试验提供信息.
科学领域:
- 老年医学 老年医学
- 临床药理学 临床药理学
- 患者安全 患者安全
背景情况:
- 经常住院和多药治疗的老年人面临药物不良事件的高风险.
- 在这个人群中,高风险药物加剧了严重药物相关问题的可能性.
- 目前的护理缺口需要创新的方法来管理弱势老年人的药物管理.
研究的目的:
- 评估临床药理和毒理 (CPT) 药物管理干预措施对高风险老年人的可行性.
- 确定CPT干预是否可以减少住院期间和之后的药物治疗问题.
- 评估干预对护理协调,生活质量和医疗保健利用的影响.
主要方法:
- 实用试点随机试验与1:1分配和盲目的结果评估.
- 纳入标准:65岁以上的成年人,>2天内科住院,之前住院,≥5种慢性药物,包括≥1种高风险药物.
- 干预包括住院患者药物标识,患者协商的处方优先级,出院协调,护理圈沟通和两次出院后的虚拟访问.
主要成果:
- 可行性结果包括招聘率,参与者保留率和干预成本.
- 临床结局侧重于药物治疗问题的数量在干预后得到改善.
- 二次结果评估了护理过渡协调,患者报告的生活质量和医疗保健利用情况.
结论:
- 有希望的可行性和临床结果可以支持使用国家平台进行最终试验.
- 专业临床药理学和毒理学专业知识的虚拟交付提供了一个可扩展的解决方案.
- 该干预措施有可能大大提高药物安全性,患者的治疗结果和老年护理的成本效益.
相关概念视频
01:28Drug Therapy
43
The advent of drug therapy has profoundly shaped modern mental health care, providing targeted treatments for a range of psychological disorders. Psychotherapeutic drugs, classified into antianxiety, antidepressant, and antipsychotic medications, address symptoms across anxiety disorders, mood disorders, and schizophrenia. While these medications have transformed patient outcomes, they require careful management due to their potential side effects and limitations.
Antianxiety Medications
Antianxiety Medications
43
01:21Factors Affecting Drug Response: Overview
2.0K
When it comes to infants and young children, they are typically administered smaller doses of medication in comparison to adults. This is primarily because their organ functions still need to fully develop, meaning their bodies are not as efficient at metabolizing or eliminating drugs. Additionally, their blood-brain barrier is more permeable than in adults. As a result, high concentrations of drugs can easily penetrate the central nervous system (CNS), potentially leading to neurological...
2.0K
01:28Current Trends in Nursing I
1.5K
Current trends in nursing include:
1.5K
01:29Documentation in Long-Term and Home Healthcare Setting
885
Documentation in long-term care facilities and home healthcare settings is crucial for ensuring continuous, coordinated, and comprehensive care for patients. Each setting has its specific documentation processes and tools:
Long-Term Care Facilities
Long-Term Care Facilities
885
01:25Types of Reports I: Hands-off Report
903
A hand-off report, also known as a change-of-shift report, is a crucial nursing process that ensures the smooth transition of patient care responsibilities between nursing staff.
Following are the key components and categories of hand-off reports:
Purpose and Process:
Following are the key components and categories of hand-off reports:
Purpose and Process:
903
01:30Guidelines for Nursing Documentation I
1.1K
Quality documentation and reporting share essential characteristics that ensure they are practical and valuable resources for those who use them. These characteristics are:
Factual:
The following points emphasize the significance of upholding accurate and unbiased documentation in healthcare.
Factual:
The following points emphasize the significance of upholding accurate and unbiased documentation in healthcare.
1.1K