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相关概念视频

Computed Tomography01:10

Computed Tomography

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Tomography refers to imaging by sections. Computed tomography (CT) is a non-invasive imaging technique that uses computers to analyze several cross-sectional X-rays to reveal minute details about structures in the body.
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...
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Magnetic Resonance Imaging01:24

Magnetic Resonance Imaging

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Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...
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Positron Emission Tomography01:29

Positron Emission Tomography

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Positron emission tomography (PET) is a medical imaging technique involving radiopharmaceuticals — substances that emit short-lived radiation. Although the first PET scanner was introduced in 1961, it took 15 more years before radiopharmaceuticals were combined with the technique and revolutionized its potential.
One of the main requirements of a PET scan is a positron-emitting radioisotope, which is produced in a cyclotron and then attached to a substance used by the part of the body...
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Imaging Studies I: CT and MRI01:14

Imaging Studies I: CT and MRI

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Introduction: MRI and CT scans are crucial advancements in medical imaging techniques, playing a vital role in diagnosing conditions related to the gastrointestinal (GI) system. Each scan serves distinct purposes, targets specific areas, and requires unique nursing duties.
Description of the Procedures
Computed Tomography (CT) scan:
Computed Tomography (CT) scans use X-ray technology to generate detailed images of bones, organs, and tissues. During the scan, the patient lies on a moving table...
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Using Optical Coherence Tomography and Optokinetic Response As Structural and Functional Visual System Readouts in Mice and Rats
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在多发性硬化症中进行光学连贯性断层扫描.

Amin Najafi1, Negin Ashoori2, Katayoon Hosseini2

  • 1Department of Ophthalmology, Ardabil University of Medical Sciences, Ardabil, Iran.

Medical hypothesis, discovery & innovation ophthalmology journal
|April 11, 2024
PubMed
概括
此摘要是机器生成的。

光学连贯断层扫描 (OCT) 在多发性硬化症 (MS) 患者中显示了更薄的视网膜神经纤维层. 年龄和性别对这些OCT测量有影响,这表明OCT是MS的潜在查工具.

关键词:
生物标志物生物标志物扩散性硬化症是一种扩散性硬化症.健康的参与者是健康的参与者.ms (多发性硬化症) 是一种疾病.神经纤维神经纤维的神经纤维.视觉神经元的光学神经元.光学连贯性断层扫描 (optical coherence tomography) 是一种光学连贯性断层扫描技术.

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科学领域:

  • 眼科医生 眼科 眼科
  • 神经学 神经学
  • 生物标志物发现发现

背景情况:

  • 多发性硬化症 (MS) 是一种慢性神经退行性疾病,影响中枢神经系统.
  • 光学连贯断层扫描 (OCT) 正成为MS的潜在生物标志物.
  • 视网膜神经纤维层厚度 (RNFLT) 是一个关键的OCT测量.

研究的目的:

  • 使用OCT测量环囊细胞RNFL厚度 (cpRNFLT).
  • 为了比较健康个体中的cpRNFLT与MS患者 (带有和没有视神经炎) 的情况.

主要方法:

  • 对多发性硬化患者和健康对照者的横截面研究.
  • 使用扫描来源的OCT测量总,上部和下部cpRNFLT.
  • 人口统计数据和多发性硬化病史的记录.

主要成果:

  • 与对照组相比,MS患者 (有/没有视神经炎) 的cpRNFLT显著较薄 (P < 0.001).
  • 女性表现出比男性更厚的cpRNFLT (P < 0.05).
  • 年龄与总cpRNFLT (r = -0.41; P < 0.05) 有中度的反相关性.

结论:

  • 多发性硬化症患者表现出减少的cpRNFLT,支持OCT作为多发性硬化症查工具的潜力.
  • 年龄和性别显著影响MS中cpRNFLT测量.
  • 需要进一步的纵向和诊断准确性研究来确认OCT作为MS生物标志物的作用.