TCAR-T

Lorena García-García1,2, Elena G Sánchez1,2, Mariya Ivanova1,2

  • 1Department of Pediatric Hematology and Oncology, Hospital Infantil Universitario Niño Jesús, Madrid, Spain.

PubMed
概括

这项研究开发了一种新的仿真抗原受体-T细胞 (CAR-T) 疗法,使用GD2特异性抗体向神经母细胞瘤. 来自带血的CAR-T细胞显示出有前途的抗瘤活性,表明固体瘤治疗的潜力.

相关概念视频

T Cell Activation and Clonal Selection01:22

T Cell Activation and Clonal Selection

T cells are integral to our adaptive immune system, recognizing and effectively responding to foreign antigens. T cell activation and clonal selection are pivotal in orchestrating this immune response. This article elucidates these mechanisms, detailing the roles of cluster of differentiation (CD) markers, major histocompatibility complex (MHC) molecules, costimulatory signals, and the process of clonal selection.
Naive T cells that have not yet encountered an antigen express two primary CD...
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