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血栓栓塞栓预防中使用的积极和被动技术对术后期静脉流速的影响
István Zsenák1, Alexandra Makai2, Gabriella Kiss3
1Doctoral School of Health Sciences, University of Pécs, Pécs, Hungary.
Frontiers in physiology
|April 11, 2024
概括
机械血栓栓塞预防显著增加静脉流速. 数学建模估计了恢复时间,显示了积极和被动干预措施的更长的效果,特别是在半侧.
科学领域:
- 血管医学 血管医学
- 生物医学工程 生物医学工程
- 数学建模的数学建模
背景情况:
- 机械血栓栓塞预防方法用于增加静脉流量和减少静脉静止.
- 现有研究评估了干预后的直接时间 (1-10分钟).
- 由于这些干预措施增加了静脉流速的持续时间,临床试验并没有很好地定义.
研究的目的:
- 应用数学技术来估计机械血栓塞栓预防后静脉流量增加的持续时间.
- 为了确定干预后峰值静脉流速恢复到静止状态的时间.
主要方法:
- 一项对25名中风后患者的调查 (平均年龄57.2±6.3岁,52%是男性).
- 使用多普勒超声波 (HADECO BIDOP ES-100V II,8 MHz) 在大腿静脉中测量的静脉血流速度峰值.
- 静脉血流速度的变化,用微软Excel中的最小方程方法估计.
主要成果:
- 峰值静脉流速的下降遵循一个对数函数.
- 休息静脉流速恢复时间: 26.8分钟 (完整的四肢),85.1分钟 (半侧) 后,积极的预防.
- 静止流速恢复时间: 131.9 分钟 (被动调动), 137.7 分钟 (共识效应) 后被动调动.
结论:
- 一个基本的数学函数可以从干预后15分钟的测量中估计静脉流速恢复时间.
- 积极和被动的机械血栓栓塞预防表明,对静脉流速有持续的,长期的影响.
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