对于性结肠炎的NSQIP5因素修改的脆弱指数和ileal囊解剖后的并发症
Dakota T Thompson1, Ethan G Breyfogle1, Catherine G Tran1
1Department of Surgery, University of Iowa Hospitals & Clinics, 200 Hawkins Drive, Iowa City, IA 52241, United States of America.
修改后的脆弱性指数 (mFI-5) 在预测慢性性结肠炎 (CUC) 患者的术后并发症时具有有限的效用,这些患者接受了囊-门缩 (IPAA). 需要进一步的研究,以更好地评估这个群体的脆弱性.
科学领域:
- 结肠直肠手术 结肠直肠手术
- 手术结果研究研究.
- 炎症性肠道疾病是什么
背景情况:
- 虚弱与不良的术后结果有关.
- 五因素修改的脆弱性指数 (mFI-5) 是一个客观的脆弱性指标.
- 它在慢性性结肠炎 (CUC) 患者的有效性未确立,这些患者接受了囊-门缩 (IPAA).
研究的目的:
- 评估mFI-5在测量脆弱性的有效性.
- 分析mFI-5对接受IPAA的CUC患者术后发病率的影响.
主要方法:
- 利用美国外科医生学院国家外科质量改进计划 (ACS-NSQIP) 的向生殖切除数据库.
- 根据5次手术前诊断计算的mFI-5.
- 分析了mFI-5和轻微/重大术后发病率之间的关联.
主要成果:
- 包括1454名CUC患者 (平均年龄38岁).
- 87%的人患有mFI-5=0,11%的人患有mFI-5=1,2.5%的人患有mFI-5≥2.5.
- mFI-5≥2与轻微并发症 (OR=2.29,p=0.049) 相关,但没有重大并发症 (p=0.860).
结论:
- 对CUC的IPAA与显著的术后发病率有关.
- 单独mFI-5对识别患有虚弱相关并发症的高风险患者的实用性有限.
- 对于这一患者群体,需要更相关的脆弱性评估工具.
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