甲尼尔-tRNA合成酶的合成和校对活动是抗生素持久性的决定因素

Whitney N Wood1,2, Miguel Angel Rubio1, Lorenzo Eugenio Leiva2

  • 1Department of Microbiology, The Ohio State University, Columbus, OH, United States.

PubMed
概括

细菌抗生素持久性是一种生存策略,由metG基因的突变增强. 这些变化扰乱了蛋白质合成和同氨酸代谢,增加了在抗生素暴露期间的细菌存活率.

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