在患有唐氏综合征的幼儿中,用于阻塞性睡眠呼吸暂停的低音神经刺激
Isaac Wasserman1, Douglas J Chieffe1, Kevin S Gipson2,3,4
1Department of Otolaryngology, Massachusetts Eye and Ear, Boston, Massachusetts.
Pediatrics
|April 11, 2024
概括
低分泌神经刺激 (HGNS) 为患有唐氏综合征 (DS) 和阻塞性睡眠呼吸暂停 (OSA) 的幼儿提供了潜在的治疗方法,这些儿童对其他疗法不耐药. 本案例研究强调了在4岁儿童中成功植入HGNS,表明了其在这个人群中的可行性和益处.
科学领域:
- 儿科耳鼻喉科 儿科耳鼻喉科
- 神经学 神经学
- 遗传学 遗传学是一种遗传学.
背景情况:
- 阻塞性睡眠呼吸暂停 (OSA) 在患有唐氏综合征 (DS) 的儿童中非常普遍.
- 像腺切除术和正气道压力 (PAP) 这样的标准治疗方法在这个人群中通常具有有限的成功或不良耐受性.
- 持续的OSA会对患有DS的儿童的健康和认知发展产生负面影响.
研究的目的:
- 评估低分泌神经刺激 (HGNS) 在患有唐氏综合征和治疗不耐用的OSA的非常年轻儿童的可行性和结果.
- 探索HGNS在患有DS的儿科患者中的潜在神经认知益处.
主要方法:
- 一个4岁男孩患有DS和耐火性OSA的案例报告.
- 成功植入一个低分泌神经刺激 (HGNS) 装置.
- 对解剖学可行性和术后结果的评估,包括设备批量.
主要成果:
- 在一个患有DS的4岁孩子身上,HGNS装置在没有并发症的情况下被植入.
- 植入导致了最小的术后体积.
- 该案例表明,HGNS对于患有DS和耐火性OSA的年幼儿童来说是一个可行的选择.
结论:
- 低分泌神经刺激 (HGNS) 可能是患有唐氏综合征 (DS) 和阻塞性睡眠呼吸暂停 (OSA) 的幼儿对常规疗法的不反应的安全有效的治疗选择.
- 这一案例支持进一步调查DS患者中耐火性儿科OSA的HGNS,有助于临床医生和家庭之间的共享决策.
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