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在线粒体胆固醇中介的降低,通过提高Jmjd3的调节,在巨细胞中产生抗炎反应

Zeina Salloum1, Kristin Dauner1, Yun-Feng Li2

  • 1Chronic Disease Program, Ottawa Hospital Research Institute, Ottawa, Canada.

eLife
|April 11, 2024
PubMed
概括

类药物降低了巨细胞中的胆固醇,增加了JMJD3的表达. 这种表观遗传修饰增强了抗炎反应,并改变了巨细胞激活通路,揭示了他类药物的关键机制.

关键词:
细胞生物学 细胞生物学胆固醇 胆固醇 胆固醇 是一种这是一种炎症炎症炎症炎症.巨细胞是什么?巨细胞是什么?这里是鼠标鼠标鼠标鼠标鼠标鼠标.

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