胸裂和胸部挖掘:一个被忽视的先天性关联?
Liliana Piro1,2, Federica Lena3,4, Arianna Roggero3,4
1Pediatric Surgery Department, IRCCS Istituto Giannina Gaslini, Via Gerolamo Gaslini 5, 16147, Genoa, Italy. lilli.me@libero.it.
Pediatric surgery international
|April 11, 2024
概括
椎裂 (SC) 患者经常患有乳腺挖掘 (PE),这表明存在先天性联系. 建议在SC修复期间早期考虑PE预防或治疗.
科学领域:
- 胸部形 胸部形 胸部形
- 遗传异常 是一种先天性异常.
- 儿科手术 儿科手术
背景情况:
- 椎裂 (SC) 是一种罕见的形,有2.6-5%的病例与部挖掘 (PE) 相关.
- SC和PE之间的先天性联系,或者SC修复是否影响PE发展,尚不清楚.
研究的目的:
- 调查SC患者潜在的PE频率更高的可能性.
- 评估SC患者的PE发生率,进展和治疗方法.
主要方法:
- 在2006年至2022年期间接受治疗的8名SC患者的回顾性研究.
- 对SC修复前CT扫描进行分析,计算哈勒指数 (HI) 和校正指数 (CI).
- 将SC患者的CI与对照组进行比较.
主要成果:
- 8名SC患者中有7名 (87.5%) 患有不同严重程度的同时发生的PE.
- 在SC和对照组之间观察到手术前CI的显著差异 (p < 0.00001).
- 前列腺发育的管理包括观察胸膜整形;在最近的两个案例中,试图同时预防/治疗前列腺发育.
结论:
- 研究结果表明,PE和SC之间的关联被低估了.
- 脊髓瘤患者可能具有先天性易患PE的倾向,可能因脊髓瘤修复后的生长而加剧.
- 在SC修复期间应考虑PE预防或治疗.
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