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相关概念视频

Radiological Investigation I: X-ray and CT01:30

Radiological Investigation I: X-ray and CT

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Radiological investigations, including X-rays and computed tomography (CT) scans, are critical for diagnosing and evaluating various medical conditions. These imaging techniques provide valuable insights into the body's internal structures, aiding in the detection of abnormalities, assessment of disease progression, and development of treatment strategies. This article delves into two primary radiological investigations, chest X-rays and CT scans, outlining their purpose, procedures, and...
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Radiological Investigation III: Pulmonary Angiogram and PET Scan01:13

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Radiological investigations are paramount in the diagnosis and management of various pulmonary diseases. Two essential investigations are the Pulmonary Angiogram and the Positron Emission Tomography (PET) Scan.
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A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...
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Radiological Investigation II: MRI and Ventilation Perfusion Scan01:30

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Description
Magnetic Resonance Imaging (MRI) and Ventilation Perfusion Scans are two radiological investigations that offer detailed diagnostic images of the body, particularly lung structures.
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German physicist Wilhelm Röntgen (1845–1923) was experimenting with electrical current when he discovered that a mysterious and invisible "ray" would pass through his flesh but leave an outline of his bones on a screen coated with a metal compound. In 1895, Röntgen made the first durable record of the internal parts of a living human: an "X-ray" image (as it came to be called) of his wife’s hand. Scientists worldwide quickly began their own experiments with...
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Positron Emission Tomography (PET) is a medical imaging technique that provides crucial insights into the body's physiological functions at a molecular level. It is an indispensable resource for diagnosing, staging, and monitoring various illnesses, notably cancer, neurological disorders, and cardiovascular conditions.
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Imaging Studies for Cardiovascular System III: X-Ray01:20

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The most common cardiovascular diagnostic test is an X-ray. It produces images of the heart, blood vessels, and adjacent structures.
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An X-ray, or radiograph, is a non-invasive method that uses ionizing radiation to take images of internal structures. It is mainly used in cardiac imaging to examine the heart, lungs, and major blood vessels, aiming to identify abnormalities in the heart's size, shape, and position, such as heart failure, congenital defects, and vascular...
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Real-Time, Two-Color Stimulated Raman Scattering Imaging of Mouse Brain for Tissue Diagnosis
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放射科医生使用的RAS疗法

Atsuhiko Handa1, Yuko Tsujioka1, Gen Nishimura1

  • 1From the Department of Radiology, Boston Children's Hospital, Harvard Medical School, 300 Longwood Ave, Boston, MA 02115 (A.H., S.A.C.); Department of Radiology, Keio University School of Medicine, Tokyo, Japan (Y.T., T.N., M.J.); Department of Radiology, Tokyo Metropolitan Children's Medical Center, Tokyo, Japan (Y.T., T.K.); Department of Radiology, Musashino-Yowakai Hospital, Tokyo, Japan (G.N.); and Department of Radiology, University of Iowa Hospitals and Clinics, Iowa City, Iowa (T.H., T.S.S., Y.S.).

Radiographics : a review publication of the Radiological Society of North America, Inc
|April 11, 2024
PubMed
概括
此摘要是机器生成的。

拉索病是一种罕见的遗传疾病,由Ras/MAPK路径突变引起. 放射科医生必须了解它们的重叠成像特征,以便为多学科的患者护理提供帮助.

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科学领域:

  • 遗传学 是一个遗传学.
  • 分子生物学分子生物学
  • 放射学 放射学是一门学科.

背景情况:

  • 拉索病是一组罕见的遗传综合征.
  • 它们源于调节Ras/mitogen激活蛋白激酶 (MAPK) 信号通路的基因突变.
  • 总的来说,RAS病症影响1000名新生儿中的1名,具有重叠的临床特征.

研究的目的:

  • 为了引入RASopathies的概念.
  • 要突出主要RASopathies之间的成像相似之处和差异.
  • 强调放射科医生意识在多学科护理中的重要性.

主要方法:

  • 关于主要RAS病变的综述.
  • 对重叠和多样化的成像特征的分析.
  • 强调Ras/MAPK通路调节失调.

主要成果:

  • 由于Ras/MAPK通路失调,RAS病变具有共同的临床和成像特征.
  • 在RASopathies内部和跨越RASopathies之间存在显著的表型变异性.
  • 瘤,无论是良性还是恶性,都与某些RASopathies有关.

结论:

  • 放射科医生必须了解RASopathies,以获得有效的多学科护理.
  • 图像检测在诊断和管理RAS病症中起着至关重要的作用.
  • 针对Ras/MAPK通路的药物显示出治疗RAS病变的潜力.