使用矩阵分解进行细胞细胞通信的无监督推断的协议

Yi Liu1, Xiao Chang2, Xiaoping Liu3

  • 1Key Laboratory of Systems Health Science of Zhejiang Province, School of Life Science, Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences, Hangzhou 310024, China; Institute of Statistics and Applied Mathematics, Anhui University of Finance and Economics, Bengbu 233030, China; Institute of Fundamental and Frontier Sciences, University of Electronic Science and Technology of China, Chengdu 610054, China.

STAR protocols
|April 11, 2024
PubMed
概括

这项研究介绍了矩阵分解推断细胞-细胞通信 (MDIC3) 的新方法,用于对细胞-细胞信号的无监督分析. 在任何物种的单细胞数据中,MDIC3确定了关键的联体受体相互作用.