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Updated: Aug 3, 2026

A Multiplexed Luciferase-based Screening Platform for Interrogating Cancer-associated Signal Transduction in Cultured Cells
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通过测试对照组样本来增加查试验的功率:应用于多种癌症检测查

Hormuzd A Katki1, Philip C Prorok2, Philip E Castle1,2

  • 1Division of Cancer Epidemiology and Genetics, Department of Health and Human Services, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.

Journal of the National Cancer Institute
|April 11, 2024
PubMed
概括

使用对照组样本的预期效应 (IE) 分析显著提高了癌症查试验的实力. 这种方法可以减少样本大小或加速试验,特别是在多种癌症检测 (MCD) 测试中.

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Combination Therapies and Personalized Medicine02:50

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Combining two or more treatment methods increases the life span of cancer patients while reducing damage to vital organs or tissue from the overuse of a single treatment. Combination therapy also targets different cancer-inducing pathways, thus reducing the chances of developing resistance to treatment.
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...