怀孕早期维生素D不足的发生率-新加坡的一项研究
Chua Zu'Er Amelia1, Chan Hiu Gwan2,3, Tan Shu Qi1
1Department of Obstetrics and Gynaecology, KK Women's and Children's Hospital, Singapore, Singapore.
PloS one
|April 11, 2024
概括
维生素D缺乏症在新加坡的孕妇中非常普遍,只有2.2%的孕妇有足够的维生素D水平. 体重和年龄等因素会影响维生素D的状况,强调需要进行产前查和补充.
科学领域:
- 产科和妇科 产科和妇科
- 内分泌学 在内分泌学.
- 营养科学 营养科学
背景情况:
- 维生素D对于骨和矿物质代谢至关重要.
- 怀孕期间维生素D水平较低与不良的产科和新生儿结局有关.
- 在新加坡,关于怀孕早期维生素D状况的数据有限.
研究的目的:
- 为了确定新加坡第一季度孕妇中维生素D缺乏症的患病率.
- 为了探索与这种人群中维生素D水平相关的因素.
主要方法:
- 在93名孕妇的第一个产前检查期间,测量了血25 ((OH) D度.
- 参与者根据维生素D充足程度 (充足,不足,中度缺乏,严重缺乏) 进行了分层.
- 分析了与体重,年龄和多维生素补充剂的关联.
主要成果:
- 只有2.2%的女性有足够的维生素D水平 (≥30 ng/ml).
- 体重较高与维生素D缺乏的可能性增加相关.
- 较年长的母亲年龄与缺乏症的可能性较低有关.
- 经概念性多维生素补充与2.10 ng/ml的平均维生素D水平更高有关.
结论:
- 在新加坡,维生素D不足是怀孕第一季度的一个重要问题.
- 在产前护理中应考虑查维生素D水平并推补充剂.
- 需要进一步的研究来调查低维生素D与产科/新生儿并发症之间的关联.
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