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Updated: Jun 28, 2025

Author Spotlight: Uncovering the Role of Mitochondrial Calcium Phosphate in Heart Failure and Bioenergetics
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心血管疾病中的机械应激诱导的线粒体功能障碍:新的机制和治疗点

He Ren1, Weiyi Hu2, Tao Jiang3

  • 1Institute of Mechanobiology & Medical Engineering, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, 800 Dongchuan Road, Minhang, Shanghai 200240, China; Key Laboratory for Biomechanics and Mechanobiology of Ministry of Education, School of Biological Science and Medical Engineering, Beihang University, Beijing 100083, China.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
|April 11, 2024
PubMed
概括

机械压力通过引起线粒体功能障碍,导致心血管疾病 (CVD). 了解这些机制可能会导致心力衰竭和动脉样硬化的新治疗点.

关键词:
一个心肌细胞.心血管疾病 (CVD) 是一种心血管疾病.周期性拉伸是循环性的.内皮细胞 (ECs) 是一种内皮细胞.能量代谢 能量代谢机械应力 机械应力 机械应力线粒体功能障碍 线粒体功能障碍反应性氧物种 (ROS) 是一种反应性氧物种.减少氧化物的控制控制.剪切压力压力是什么血管光滑肌细胞 (VSMCs) 是一种

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