在被诊断患有马内分泌系统疾病的马匹中,艾弗梅克的性能
M K Nielsen1, C A Finnerty1, N E Ripley1
1Maxwell H. Gluck Equine Research Center, Department of Veterinary Science, University of Kentucky, 1400 Nicholasville Rd, Lexington, KY 40503, USA.
Veterinary parasitology
|April 11, 2024
概括
像胰岛素失调 (ID) 和垂体部分中间功能障碍 (PPID) 这样的马类内分泌疾病并没有显著影响老年马的甲胺疗效. 然而,在一些患有ID或PPID的马群中,观察到卵子重新出现的时间缩短,这表明需要进一步研究.
科学领域:
- 兽医寄生虫学 兽医寄生虫学
- 马类内分泌学 马类内分泌学
背景情况:
- 马类动物的杀性能通常通过便卵数减少测试 (FECRT) 和蛋再出现周期 (ERP) 来测量.
- 现有的数据主要集中在年轻的马匹上,对老年马匹的信息有限,特别是那些患有内分泌疾病的马匹,如胰岛素失调 (ID) 和垂体部分中间功能障碍 (PPID).
- 患有ID和PPID的马可能更容易受到寄生虫感染的感染,这可能会影响杀虫剂疗效的测量.
研究的目的:
- 评估对老年马类马匹的抗马体菌素 (equine cyathostomins) 的艾弗梅克丁疗效,包括那些有或没有PPID和/或ID的马匹.
- 为了确定内分泌疾病是否会影响老年马的FECRT和ERP测量.
主要方法:
- 研究群体包括老年马,包括患有ID,PPID或两者的老年马和健康的对照.
- 在一项疗效研究中,所有阳性强基卵数的马都接受了ivermectin (200μg/kg).
- 在治疗前,治疗后两周,并在八周内每周监测便卵数量,遵循世界兽医寄生虫学协会关于FECRT和ERP确定指南.
主要成果:
- 艾弗梅克丁的疗效很高,在治疗后两周,所有组的平均卵数减少了99.7%或更高.
- 在ID组六周和PPID/ID组七周后观察到卵子再次出现.
- PPID和健康的对照组表现出一个卵子重新出现的周期为八周. 两组之间没有发现卵数水平的显著差异.
结论:
- 在老年马群中,无论内分泌状况如何,艾弗梅克仍然对马类细胞质素具有高度有效性.
- 虽然由于小群体规模而没有统计学意义,但ID和PPID马的缩短ERP需要进一步调查.
- 内分泌疾病可能会微妙地影响甲虫的性能,因此需要继续在这一领域进行研究.
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