在患有 pituitary pars intermediate 功能障碍的马匹中,强力卵子流失和卵子重新出现的时期
Adelaina Horner1, Nicholas J Bamford2, Michael J Stear3
1Institute of Innovation, Science and Sustainability, Federation University, Victoria 3350, Australia.
Veterinary parasitology
|April 11, 2024
概括
患有脑垂体中介性干扰 (PPID) 的马在治疗后表现出更高的强便卵数 (FEC) 和更短的卵再出现周期,这表明免疫力受损. 个人FEC监测对于PPID马的寄生虫管理至关重要.
科学领域:
- 兽医医学 兽医医学 兽医医学
- 内分泌学 在内分泌学.
- 寄生虫学的寄生虫学
背景情况:
- 垂体半介质功能障碍 (PPID) 是老马常见的内分泌疾病.
- 与PPID相关的免疫功能障碍可能会增加对寄生虫感染的易感性.
- 有限的数据存在于PPID和马中的强基菌感染之间的关系.
研究的目的:
- 为了调查与对照马相比,患有PPID的马是否具有更高的强基便卵数 (FEC).
- 为了评估PPID对寄生虫蛋的影响和14周的抗虫治疗疗效.
- 为了评估PPID和对照马的卵子再出现期 (ERP),用虫治疗后进行对照治疗.
主要方法:
- 根据临床症状和ACTH水平,马被分为PPID (n=14) 和对照 (n=31) 组.
- 便样本被采集用于FEC的确定,在治疗前和每两周一次治疗后.
- 使用通用线性混合建模来比较FEC在不同组之间,控制年龄.
主要成果:
- 与对照组相比,PPID马在治疗后的56日和70日显示出明显更高的FEC平均值.
- 在PPID组中,从第14天到第98天的累积FEC明显高于PPID组.
- PPID马的ERP (56日) 比对照马的ERP (70日) 短,30%的马在42日达到200个EPG以上.
结论:
- PPID马可能具有免疫反应受损或宿主-寄生虫关系发生变化,导致强基FEC增加和更快的再感染.
- 尽管存在群体差异,但个人FEC监测对于确定PPID马的甲虫治疗需要至关重要.
- 这些发现支持为患有PPID的马匹量身定制的寄生虫管理策略,强调个体监测.
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