补充卡西斯聚没有影响健康中年妇女更年期症状:一个随机,双盲,平行组,安慰剂控制的随机试验
Mayumi Ohtsuka1, Tohru Yamaguchi2, Sachiko Oishi1
1Biological Science Research Laboratories, Kao Corporation, 2-1-3 Bunka, Sumida, Tokyo 131-8501, Japan.
Nutrition research (New York, N.Y.)
|April 11, 2024
概括
在为期4周的试验中,卡西斯多 (CaP) 补充剂并没有缓解更年期症状. 然而,稍后的观察期显示,CaP组的热和出汗减少,这表明需要进一步研究的潜在益处.
科学领域:
- 更年期研究研究更年期研究.
- 营养科学 营养科学
- 临床试验中的临床试验.
背景情况:
- 更年期过渡涉及激素变化,导致血管运动症状,如热和神经精神问题.
- 卡西斯聚烯 (CaP) 被研究其改善微循环和血管放松的潜力,从而减轻更年期症状.
研究的目的:
- 评估卡西斯多 (CaP) 补充剂在减轻健康日本女性发热和其他更年期症状的疗效.
- 评估CAP对更年期期间和之后的生活质量,幸福感,焦虑和睡眠模式的影响.
主要方法:
- 一项随机,双盲,安慰剂对照试验与59名年龄在51岁左右的健康妇女进行,这些妇女经历了更年期症状.
- 参与者接受了400毫克/天的CaP或安慰剂4周,随后是2周的观察期.
- 症状评估包括热频率/分数,出汗,修改的库珀曼指数,WHO-5幸福指数,WHOQOL-26,STAI和OSA睡眠库存.
主要成果:
- 在4周的干预期间,在CaP和安慰剂组之间没有观察到热频率,更年期症状,生活质量,焦虑或睡眠的显著差异.
- 在干预后的2周期间,与安慰剂组相比,CaP组的热得分和出汗频率显著下降.
结论:
- 四周的每日卡西斯聚烯 (CaP) 摄入量并没有在短期内显著缓解更年期症状.
- 在干预后的时间段中,人们注意到了对热和出汗的潜在延迟益处,这需要在更大的研究中进一步调查.
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