测量患有结核性硬化综合体的幼儿的发育和行为问题
Nicole M McDonald1, Sydney Jacobs2, Carly Hyde1
1UCLA Semel Institute of Neuroscience and Human Behavior, David Geffen School of Medicine, Los Angeles, California.
Pediatric neurology
|April 11, 2024
概括
在患有结核性硬化综合体 (TSC) 的幼儿中,行为问题很普遍,随着年龄的增长而增加. 坦德检查清单有效地选TSC幼儿的这些问题,尽管建议进行修改.
科学领域:
- 儿科神经学 儿科神经学
- 神经发育障碍 神经发育障碍
- 结核性硬化综合体 结核性硬化综合体
背景情况:
- 结核性硬化综合体 (TSC) 与关联的神经精神疾病 (TAND) 检查清单对TSC的神经发育障碍进行检查.
- 现有的研究主要集中在患有TSC的老年儿童和成年人身上.
- 这项研究解决了需要了解TSC的幼儿的行为问题.
研究的目的:
- 在被诊断患有TSC的幼儿中使用TAND检查清单调查行为问题.
- 在幼儿中识别TAND检查清单响应中的与年龄相关的模式.
主要方法:
- 对90名患有TSC的幼儿 (12-36个月) 的TAND检查清单的护理人员反应进行了分析.
- 在两个TSC早期干预研究的基线访问期间收集了数据.
- 参与者被分为两个年龄组:12-23个月 (n=60) 和24-36个月 (n=30).
主要成果:
- 超过90%的护理人员报告至少有一个TAND相关的行为问题.
- 报告的担忧频率随着年龄的增长而增加.
- 语言延迟是最常见的担忧 (58.3%的年轻人,86.7%的老幼儿).
- 行为项目是相关的,但神经心理和学术项目不适合这个年龄组.
结论:
- 在患有TSC的幼儿中,TAND症状非常常见,似乎随着年龄的增长而升级.
- 坦德检查清单对于识别年轻TSC患者的行为问题是有价值的.
- 由于项目相关性问题,建议采取适应措施,例如为幼儿提供缩短的检查清单.
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