对儿童发病多发性硬化症患者的饮食摄入量及其炎症潜力的评估
Sama Bitarafan1, Feng Zhu2, Ali Mirza2
1Faculty of Medicine (Neurology), University of British Columbia and the Djavad Mowafaghian Centre for Brain Health, University of British Columbia, Vancouver, Canada; Iranian Center of Neurological Research, Neuroscience Institute, Tehran University of Medical Sciences, Tehran, Iran.
Multiple sclerosis and related disorders
|April 11, 2024
概括
患有儿科发病多发性硬化症 (PoMS) 的个人比对照群消耗的全谷物少. 饮食炎症指数在各组之间没有显著差异,这表明全谷物可能在PoMS中发挥作用.
科学领域:
- 神经学 神经学
- 营养科学 营养科学
- 流行病学 流行病学
背景情况:
- 儿科发病多发性硬化症 (PoMS) 和单相获得性脱髓化综合征 (monoADS) 是一种罕见的神经疾病.
- 饮食模式和炎症都与多发性硬化症 (MS) 病变发生有关.
- 了解儿科神经疾病中的饮食因素对于管理至关重要.
研究的目的:
- 为了比较饮食摄入量和改变饮食炎症指数 (mDII) 在患有PoMS,单一ADS和健康对照的人群中.
- 调查儿童神经疾病中饮食,mDII和疾病状况之间的关联.
主要方法:
- 一项涉及131名参与者的横截面研究 (38名PoMS,45名MonoADS,48名对照).
- 评估了饮食摄入量和mDII.
- 后勤回归分析用于检查饮食,mDII和疾病状态之间的关联.
主要成果:
- 与对照组相比,患有PoMS的个体与较低的全谷物摄入量有着适度但显著的关联 (aOR=0.964).
- 在这个队列中,修改的饮食炎症指数 (mDII) 与PoMS没有显著的关联.
- 与对照人群相比,单一ADS患者的饮食没有显著差异.
结论:
- 较低的全谷物消费与儿科发病多发性硬化症 (PoMS) 有关.
- 饮食炎症指数没有区分PoMS,monoADS和对照组.
- 研究结果表明,全谷物在饮食管理中可能发挥作用.
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