电疗法与躁狂发作后再入院时间之间的关联
Katarzyna Popiolek1, Tor Arnison1, Susanne Bejerot1
1University Health Care Research Centre, Faculty of Medicine and Health, Örebro University, Örebro, Sweden.
Acta psychiatrica Scandinavica
|April 11, 2024
概括
在躁狂发作治疗后,再入院率仍然很高. 电疗法 (ECT) 与再入院时间的延长没有显著关联,但趋势表明在一些患者中具有保护作用.
科学领域:
- 精神病学是一个精神病学.
- 临床神经科学 临床神经科学
背景情况:
- 大多数因躁狂发作住院的患者在两年内面临重新入院的困境,即使有维持治疗.
- 电疗法 (ECT) 已在其他精神疾病中减少了再入院,但其对躁狂再入院的影响尚未得到充分证实.
研究的目的:
- 调查电疗法 (ECT) 是否会增加患有躁狂发作的患者重新入院精神病房的时间.
- 确定可能从ECT中获得更大的益处的患者子组,以确定再入院率.
主要方法:
- 在瑞典 (2012-2021年) 进行了一项全国性的基于登记的观察性研究,包括所有因躁狂发作住院的患者.
- 分析涉及所有住院患者,随后采用配对样本模型,比较同一患者内的ECT与非ECT住院患者.
主要成果:
- 在12337个招生中,7.3%的学生接受了ECT. 总的来说,ECT与再入院时间没有显著的关联 (aHR 1.00).
- 在对377名患者的对分析中,ECT入院显示了较低的30天再入院率 (19.0%vs24.1%,aHR 0.75) 的趋势,尽管在统计学上不显著 (p=0.067).
结论:
- 在治疗躁狂症的住院治疗后,再入院率很高.
- 虽然在统计学上没有显著性,但电疗法 (ECT) 显示出一种趋势,即对躁狂患者的精神病再入院有保护作用,特别是在个人比较中分析时.
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