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Updated: Jun 28, 2025

Author Spotlight: Advancements in Hypoxia-Sensitive CAR-T Therapy for Enhanced Cancer Immunotherapy
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Published on: June 14, 2024

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在固体瘤中应用CAR-T细胞治疗的困境和可能的解决方案

Lihong Wang1, Lufang Zhang2, Louisa Chard Dunmall3

  • 1Department of Oncology, Air Force Medical Center, PLA, Beijing, China; National Centre for International Research in Cell and Gene Therapy, Sino British Research Centre for Molecular Oncology, State Key Laboratory of Esophageal Cancer Prevention & Treatment, School of Basic Medical Sciences, Academy of Medical Sciences, Zhengzhou University, Zhengzhou, China.

Cancer letters
|April 11, 2024
PubMed
概括

化学抗原受体T (CAR-T) 细胞疗法对血液癌症有希望,但在固体瘤中面临挑战. 本综述探讨了克服固体瘤微环境的局限性,以实现CAR-T细胞治疗的成功.

关键词:
在CART-T中,我们可以使用CAR-T.逻辑门是一个逻辑门.固体瘤是一个固体瘤.瘤微环境是一个微环境.

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