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怀孕期间的颗粒物2.5暴露和分娩后果:来自哥伦比亚的证据

Johana Márquez-Lázaro¹, Meisser Madera², Eduardo Bernabe³

¹Medicine program, TOXSA group, Corporación Universitaria Rafael Núñez, Cartagena, Colombia.

The Science of the total environment

|April 11, 2024

概括

在哥伦比亚,怀孕期间接触细颗粒物 (PM2.5) 与早产和低出生体重的风险增加有关. 这项研究强调了空气污染对中等收入国家的不良妊娠结果的影响.

科学领域:

环境健康环境健康
生殖流行病学生殖流行病学
公共卫生公共卫生

背景情况:

颗粒物 (PM2.5) 是一个重要的空气污染物,直径小于2.5微米的颗粒.
暴露于PM2.5对健康构成风险,特别是对孕妇和胎儿,有新兴证据将其与不良妊娠结果联系起来.
大多数关于PM2.5和怀孕结果的现有研究来自西方国家,需要在不同的环境中进行研究.

研究的目的:

调查哥伦比亚怀孕期间暴露于PM2.5和分娩结果之间的联系.
评估与PM2.5暴露有关的早产 (PTB) 和低出生体重 (LBW) 的特定风险.

主要方法:

一项大型队列研究包括2019年在哥伦比亚出生于15岁以上的母亲的542,800名单身儿童.
出生记录提供了关于父母,孩子和出生特征的数据.
基于卫星的月度PM2.5度估计用于评估整个怀孕期间的市级暴露;后勤回归模型分析了与PTB和LBW的关联.

主要成果:

该研究发现PTB的患病率为8.6%,LBW的患病率为8.3%.
各市镇的PM2.5平均度为18.26±3.30μg/m3.
在调整了混因素后,较高的市级PM2.5度与PTB (OR:1.05,95%CI:1.04-1.06) 和LBW (OR:1.04,95%CI:1.03-1.05) 的概率增加显著相关.

结论:

这项研究提供了来自中等收入国家的新证据,证明PM2.5暴露与不良妊娠结果之间存在积极联系.
调查结果强调了空气污染对哥伦比亚母亲和婴儿健康的公共卫生影响.
需要进一步的研究和有针对性的干预措施来缓解怀孕期间的PM2.5暴露风险.

关键词:

空气污染大气污染低出生体重低出生体重颗粒物质 2.5 颗粒物质 2.5 怀孕的结果怀孕的结果过早分娩过早分娩是什么

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