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Updated: Jun 28, 2025

Monitoring eIF4F Assembly by Measuring eIF4E-eIF4G Interaction in Live Cells
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Monitoring eIF4F Assembly by Measuring eIF4E-eIF4G Interaction in Live Cells

Published on: May 1, 2020

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与POI相关的EIF4ENIF1突变显示出翻译调节能力受损

Yuxi Ding1, Shuya Chen2, Jing Jin3

  • 1The State Key Laboratory for Complex, Severe, and Rare Diseases, SXMU-Tsinghua Collaborative Innovation Center for Frontier Medicine, Department of Basic Medical Sciences, School of Medicine, Tsinghua University, Beijing 100084, China.

Gene
|April 11, 2024
PubMed
概括

EIF4ENIF1中的遗传变异与早产卵巢缺陷 (POI) 有关. 一种新型变异,R208H,和以前识别的突变,Q842P,显示了改变的翻译调节,可能解释POI病原体. 在变异函数分析中,T&T-seq被证明是有效的.

关键词:
欧洲金融基金EIF4ENIF1过早的卵巢功能不充分转录组和转录组的测序.翻译 翻译 翻译 翻译整体外基因组测序的测序

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