在膝关节骨关节炎临床实践指南中确定的研究重点的报告形式和内容:方法论文献分析
Yicheng Gao1, Zhihan Liu1, Rui Cao1
1Beijing University of Chinese Medicine, Beijing, China.
BMJ open
|April 11, 2024
概括
膝关节骨关节炎 (KOA) 的临床实践指南经常强调研究优先事项,主要关注非药物干预. 然而,没有,有.
科学领域:
- 整形外科和运动医学
- 类风湿病学 类风湿病学
- 基于证据的医学基于证据的医学.
- 临床实践指南 临床实践指南
背景情况:
- 临床实践指南 (CPG) 开发人员能够很好地确定研究优先事项,因为他们有系统的证据综合.
- 了解膝关节骨关节炎 (KOA) CPG 的研究重点报告对于指导未来的研究和临床实践至关重要.
- 本研究系统地分析了KOA CPG中研究优先事项的报告形式和内容.
研究的目的:
- 系统地分析膝关节骨关节炎 (KOA) 临床实践指南 (CPG) 中研究重点的报告形式和内容.
- 为指南制定者和临床医生提供关于KOA研究优先事项的宝贵参考.
- 在KOA CPG中确定科研重点报告的趋势和差距.
主要方法:
- 对KOA CPG进行了一项方法论文献分析.
- 通过从2017年1月到2022年12月对六个主要数据库和相关协会的官方网站进行搜索,确定了CPG.
- 用描述性统计数据提取和总结了研究重点的报告形式和内容的数据.
主要成果:
- 在41个KOA CPG中确定了187个研究重点,其中24个CPG报告了重点.
- 超过一半的研究重点 (58.8%) 是由于缺乏证据.
- 优先事项主要集中在干预疗效 (63.8%),特别是体育活动 (17.3%),物理治疗 (16.2%),手术治疗 (14.6%) 和药物治疗 (14.1%).
结论:
- 在KOA CPG的研究重点主要集中在评估非药物干预措施上.
- 在KOA CPG中,产生和报告研究重点的标准化和全面性有很大的改进潜力.
- 研究重点的标准化报告可以提高未来KOA研究的方向和影响.
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