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Updated: Jun 28, 2025

Preparation of Tumor Antigen-loaded Mature Dendritic Cells for Immunotherapy
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Preparation of Tumor Antigen-loaded Mature Dendritic Cells for Immunotherapy

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呼吸系统综合体I调节树突细胞成熟 在人类瘤免疫微环境的模型中

Rita Turpin1, Ruixian Liu1, Pauliina M Munne1

  • 1Translational Cancer Medicine, University of Helsinki, Helsinki, Finland.

Journal for immunotherapy of cancer
|April 11, 2024
PubMed
概括

患者衍生式拓展培养 (PDECs) 模拟了晚期癌症,揭示了甲胺增强了对瘤的T细胞反应. 这个模型有助于理解患者特异性瘤免疫微环境 (TIME) 中的药物相互作用.

关键词:
乳腺新生体 乳腺新生体树突细胞 树突细胞药物评估,临床前临床免疫力,天生的免疫力.免疫调节是一种免疫调节.

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T Cell Activation and Clonal Selection01:22

T Cell Activation and Clonal Selection

T cells are integral to our adaptive immune system, recognizing and effectively responding to foreign antigens. T cell activation and clonal selection are pivotal in orchestrating this immune response. This article elucidates these mechanisms, detailing the roles of cluster of differentiation (CD) markers, major histocompatibility complex (MHC) molecules, costimulatory signals, and the process of clonal selection.
Naive T cells that have not yet encountered an antigen express two primary CD...
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