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Updated: Jun 28, 2025

Detection of Small GTPase Prenylation and GTP Binding Using Membrane Fractionation and GTPase-linked Immunosorbent Assay
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κB-Ras蛋白质是快速交换的GTPases,并通过核酸独立结合Ral GTPase激活蛋白质复合体来起作用

René Rasche1, Lisa Helene Apken2, Esther Michalke2

  • 1Institute of Biochemistry, University Münster, Germany.

FEBS letters
|April 11, 2024
PubMed
概括

κB-Ras GTPases,尽管与Ras的结构差异,但表现出水解活性,并且主要与GTP结合. 它们在Ral和NF-κB信号传递中的瘤抑制功能独立于核酸结合和开关机制.

关键词:
通过小GTPases进行GTP水解.在RalGAP中使用.癌症突变 癌症突变小型GTPases的核酸结合.κB-Ras 的意思

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