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威利斯圆对前沟通动脉动脉瘤的血液动力学参数的影响以及模型选择建议

Hyeondong Yang¹, Kwang-Chun Cho², Ineui Hong¹

¹Department of Mechanical Engineering and BK21 FOUR ERICA-ACE Center, Hanyang University, 55 Hanyangdaehak-Ro, Sangnok-Gu, Ansan, 15588, Gyeonggi-Do, Korea.

Scientific reports

|April 11, 2024

概括

选择正确的威利斯圆模型对于精确的前沟通动脉动脉瘤计算流体动力学 (CFD) 分析至关重要. 具体患者模型显示,简化的威利斯圆模型可以显著改变血液动力学结果.

科学领域:

生物医学工程生物医学工程
医疗成像医学成像
流体动力学流体动力学

背景情况:

前沟通动脉动脉瘤 (AComA) 是常见的脑血管疾病.
计算流体动力学 (CFD) 用于在ACOMA研究血液动力学.
目前的CFD研究经常使用简化或不完整的威利斯圆 (CoW) 模型.

研究的目的:

为选择合适的Cow模型提供建议,用于对AComA的CFD分析.
为了比较完整和半 CoW 模型之间的血液动力学参数和流动模式.

主要方法:

创建了五个患者特定的Cow模型与AComA.
每个模型分为完整,左半和右半配置.
进行了CFD模拟,并与流体实验进行了验证.

主要成果:

在五个案例中,四个案例中观察到来自A1部分的流入主导地位.
在一个案例中,在完整模型和半个模型之间发现了时间平均壁压力的显著差异 (62%对4.6%).
在A1和A2段的血管阻力差异对AComA流动模式产生了重大影响.

结论:

选择 CoW 模式对 AComA.A. 的 CFD 结果产生重大影响.
患者特定的因素,如血管阻力,影响流动动力学.
准确的血液动力学评估需要仔细考虑Cow模型选择,以改善动脉瘤诊断和治疗.

关键词:

前沟通动脉动脉瘤的前部沟通动脉威利斯的圆圈威利斯的圆圈计算流体动力学计算流体动力学血液动力学参数血液动力学参数血管阻力血管阻力

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