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Updated: Jun 28, 2025

Methods for the Discovery of Novel Compounds Modulating a Gamma-Aminobutyric Acid Receptor Type A Neurotransmission
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Published on: August 16, 2018

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经典的D1多巴胺受体对手SCH23390是一种功能性西格玛-1受体全调节器

Gu-Fang Zhang1, Kai-Lian Zhu1, Qi Li1

  • 1Jiangsu Key Laboratory of Neuropsychiatric Diseases and Department of Pharmacology, College of Pharmaceutical Sciences, Soochow University, Suzhou, 215123, China.

Acta pharmacologica Sinica
|April 11, 2024
PubMed
概括

作为D1多巴胺受体对手的SCH23390也在全质调节Sigma-1受体 (Sig1R). 这种相互作用影响神经元保护和GSK3β活性,揭示了SCH23390的新机制.

关键词:
在GSK3ββ中.这是SCH2339090的.西格玛-1受体是一个受体.通过全osteric 调制.药理作用药理作用的作用.

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