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Updated: Jun 28, 2025

Spatiotemporal Control of Protein Activity through Optogenetic Allosteric Regulation
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解密 S100B 体信号传输:作为集成调节器的体标TRTK-12的作用

Riya Samanta1, Xinhao Zhuang2, Kristen M Varney3

  • 1Biophysics Graduate Program, University of Maryland, College Park, Maryland 20742, United States.

Journal of chemical information and modeling
|April 12, 2024
PubMed
概括

在S100B蛋白中的Allostery是由TRTK-12调节,改变其结合亲和力和对盐度的反应. 这种干扰相互作用,揭示了药物发现至关重要的全沟通机制.

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