迷幻药和"内心治疗师":神话还是机制?
Joseph Peill1, Miriam Marguilho2, David Erritzoe1
1Division of Psychiatry, Department of Brain Sciences, Centre for Psychedelic Research, Imperial College London, London, UK.
Journal of psychopharmacology (Oxford, England)
|April 12, 2024
概括
迷幻药物使用者经常相信一个"内心的治疗师". 这项研究发现psilocybin具有更高的内在愈合效应,这也预测了抑郁症症状的减少,这表明了潜在的治疗机制.
科学领域:
- 心理药理学和精神病学
- 迷幻研究 迷幻研究
- 心理健康 治疗方法 治疗方法
背景情况:
- "内在治疗师"的概念在使用迷幻药的文化中很普遍,这表明对心灵和大脑的内在再生效应.
- 这种信念与身体在患病或受伤后的自然愈合过程相似.
研究的目的:
- 研究和评估"内在愈合"效应的概念.
- 开发和使用一个主观的评级尺度,用于感知"内在愈合"后迷幻药的管理.
主要方法:
- 在一项双盲随机对照试验中,给59名患有抑郁症的患者注射了一次高 (25毫克) 或安慰剂 (1毫克) 剂量的psilocybin.
- 患者完成了一个主观评分项目,评估他们感知到的"内在愈合"效果.
主要成果:
- 与安慰剂组相比,在高剂量psilocybin后报告了更高的"内心治疗者"得分 (p < 0.001).
- 在高剂量组中",内心治疗师"得分与治疗后两周抑郁症状的减少有关.
结论:
- 这项研究为通过迷幻药激活内在愈合机制的概念提供了经验支持.
- 虽然在科学上还处于新生阶段,但这些发现表明",内心治疗师"现象在抑郁症的迷幻研究中需要进一步调查.
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