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Updated: Jul 15, 2026

LERLIC-MS/MS for In-depth Characterization and Quantification of Glutamine and Asparagine Deamidation in Shotgun Proteomics
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细胞外L-阿斯巴拉金酶合成细菌氨酸 隔离,优化和特征从海洋盐沉积物来源

Mugip Rahaman Abdul Wahab1, Thirunavukkarasu Palaniyandi1,2, John Wyson3

  • 1Department of Biotechnology, Dr. M.G.R Educational and Research Institute, Chennai, Tamil Nadu, India.

Avicenna journal of medical biotechnology
|April 12, 2024
PubMed
概括

研究人员在海洋沉积物中发现了Bacillus niacini细菌,能够产生酶L-asparaginase. 这种酶对于癌症治疗至关重要,为大规模生产和新的医疗应用提供了潜力.

关键词:
亚斯巴拉奇纳酶是一种亚斯巴拉基因 (Aspragine) 是一种尼雅菌是尼雅菌的一种.聚合酶连锁反应的发生.

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Penicillin, one of the earliest and most widely used antibiotics, is produced industrially by the filamentous fungus Penicillium chrysogenum. Large stirred-tank bioreactors ranging from tens to hundreds of thousands of liters maintain tightly controlled temperature, pH, and dissolved oxygen conditions to support fungal metabolism and maximize antibiotic yield. Penicillin is a secondary metabolite, synthesized primarily during the stationary growth phase, which requires a carefully managed...