作为严重登革热发烧的预测因素的APRI
Ajith K Jayachandran1, Vincy Nelson2, K Anisha1
1Department of Emergency Medicine, Travancore Medical College, Kollam, Kerala, India.
Journal of family medicine and primary care
|April 12, 2024
概括
AST/血小板比率指数 (APRI) 可以预测严重的登革热,较高的值表明风险增加. 升高的APRI也与更长的住院时间以及登革热患者更需要血小板输血有关.
科学领域:
- 医学研究 医学研究
- 肝病学 肝病学是一种肝病学.
- 传染性疾病 传染性疾病
背景情况:
- AST/血小板比率指数 (APRI) 建立用于评估肝纤维化.
- 有限的研究探索了APRI在预测严重登革热方面的潜力.
- 登革热流行需要在医疗保健中有效地分配资源.
研究的目的:
- 评估AST/血小板比率指数 (APRI) 作为严重登革热的预测指标.
- 为了确定APRI和住院时间之间的关联.
- 评估APRI与血小板输血需要之间的关系.
主要方法:
- 采用了回顾性横截面研究设计.
- 从向紧急医疗部门报告的患者收集了数据.
- 包括那些阳性登革热NS1抗原或IgM抗体测试的患者.
主要成果:
- 在预测严重登革热方面,APRI > 3.2 显示了69.2%的灵敏度和84.2%的特异性.
- 患有APRI> 3.2的患者平均住院时间为5.47天 (P = 0.005).
- 需要血小板输血的患者中有很大一部分 (81.8%) 的APRI>3.2 (P = 0.00).
结论:
- APRI是预测严重登革热的有价值且易于计算的指数.
- 超过3.2的APRI值有效地识别出患有严重结局风险较高的患者.
- 在登革热爆发期间,APRI作为管理医院资源和患者护理的有用工具.
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