身体活动可以改善轻度认知障碍或阿尔茨海默病患者的视觉空间工作记忆:系统性审查和网络元分析
Jie Deng1, Hong Wang2, Tingting Fu1
1College of Physical Education, Southwest University, Chongqing, China.
Frontiers in public health
|April 12, 2024
概括
身体活动可以改善轻度认知障碍和阿尔茨海默病的视觉空间工作记忆. 对于轻微的认知障碍,心身炼是最好的,而有氧运动对阿尔茨海默病是最佳的.
科学领域:
- 神经科学是一个神经科学.
- 老年学是一门学科.
- 运动生理学 运动生理学
背景情况:
- 轻度认知障碍 (MCI) 和阿尔茨海默病 (AD) 与认知功能的显著下降有关,包括视觉空间工作记忆.
- 确定有效的干预措施来缓解这些认知缺陷对于改善受影响个体的生活质量至关重要.
- 身体活动在认知增强方面表现有前途,但需要针对特定神经退行性疾病提供量身定制的建议.
研究的目的:
- 进行网络元分析,以确定身体活动对MCI和AD患者视觉空间工作记忆的影响.
- 根据其有效性,为患有MCI和AD的个人确定和提出量身定制的运动干预措施.
主要方法:
- 进行了频率网络元分析,比较了各种运动干预措施.
- 进行了子组分析,以探索影响干预有效性的调节变量.
- 包括34篇文章的数据,涉及3074名参与者 (1537名患有MCI,1537名患有AD).
主要成果:
- 在MCI组中,心身运动是改善视觉空间工作记忆的最有效的干预措施 (SMD = 0.61).
- 有氧运动被确定为阿尔茨海默症组的最佳干预措施 (SMD = 0.39).
- 包括的研究平均质量分数为6.6-6.75,并通过了不一致性测试.
结论:
- 对于患有MCI的人来说,建议在3个月以上的时间内以中等强度炼3+次/周60+分钟/次,包括心身,多元组件,抵抗或有氧运动.
- 对于患有阿尔茨海默病的人来说,建议每周两次进行中度强度运动,持续90+分钟/次,持续3个月以上,包括有氧运动或抵抗运动.
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