传统中医药在糖尿病外围神经病治疗中的证据映射
Yujie Fu1, Yiming Wang2, Zhenghong Li3
1Graduate School, Beijing University of Chinese Medicine, Beijing, China.
Frontiers in pharmacology
|April 12, 2024
概括
这项研究绘制了针对糖尿病外围神经病变 (DPN) 传统中医 (TCM) 临床试验的证据. 研究结果揭示了常见的TCM治疗方法和评估方法,建议在管理DPN方面改进研究和临床实践的领域.
科学领域:
- 综合医学是一个整体的医学.
- 神经学 神经学
- 内分泌学 在内分泌学.
背景情况:
- 糖尿病外围神经病变 (DPN) 是一种影响生活质量的严重糖尿病并发症.
- 临床随机对照试验 (RCT) 对于评估DPN治疗至关重要.
- 传统中医 (TCM) 为DPN提供了潜在的治疗方法.
研究的目的:
- 使用证据映射方法阐明TCM治疗DPN的证据分布.
- 分析出版物中的趋势,研究尺度,干预类型和DPN治疗中TCM的评估指标.
- 确定研究缺口,并为DPN的TCM提供未来的方向.
主要方法:
- 从2017年1月到2022年10月,对多个数据库 (Wanfang,CNKI,VIP,SinoMed,PubMed,Web of Science,Cochrane Library) 进行了全面的文献搜索.
- 从1,229个已识别的TCM中对DPN进行选择和数据提取.
- 使用描述性文本,表格和泡泡图表来可视化趋势的证据映射分析.
主要成果:
- 对DPN的TCM进行了广泛的研究,出版趋势稳定,样本大小小小.
- 常见的TCM干预措施包括口服和外部配方.
- 主要结局措施侧重于神经生理学,疗效率,症状和神经病症评分,仅限于心理状态和ABI.
结论:
- 目前的RCT强调了TCM在管理糖尿病并发症 (如DPN) 的潜力.
- 需要推进的领域包括改进研究方法,扩大干预多样性和扩大评估标准.
- 这些发现旨在指导未来的研究和TCM的临床应用.
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