印度尼西亚成年人结核病的可修改和不可修改的风险因素:系统性审查和元分析
Nindrea Ricvan Dana1, Susanti Rika1,2, Indika Pudia M1
1Department of Medicine, Faculty of Medicine, Universitas Negeri Padang, Bukittinggi, 26181, Indonesia.
African journal of infectious diseases
|April 12, 2024
概括
控制结核病 (TB) 需要了解印度尼西亚的风险因素. 这次审查确定了家庭病史,家庭接触,营养不良,通风不良,糖尿病,吸烟和低收入是预防结核病战略的关键因素.
科学领域:
- 公共卫生 公共卫生
- 流行病学 流行病学
- 传染病控制和控制传染病
背景情况:
- 结核病 (TB) 仍然是印度尼西亚的一个重大公共卫生挑战.
- 有效的结核病控制需要了解社区内的决定性因素.
- 对结核病风险因素的全面审查对于加速预防计划至关重要.
研究的目的:
- 确定和分析与居住在印度尼西亚的成年人结核病 (TB) 相关的可修改和不可修改的风险因素.
- 为针对性结核病预防战略提供基于证据的见解.
主要方法:
- 进行了系统的元分析,审查了2000年1月至2023年12月期间发表的研究.
- 分析了来自PubMed,ProQuest和Google Scholar的数据,以计算95%信心区间 (CI) 的聚合几率比率 (POR).
- 统计分析包括固定和随机效应模型,森林地块和使用Begg和Egger测试的偏差评估.
主要成果:
- 结核病 (不可修改) 的家族病史显示显著的POR为6.08 (95% CI 2.99-12.34).
- 主要可修改的风险因素包括家庭接触 (POR 6.01),营养不良 (POR 5.86),通风不足 (POR 5.57),糖尿病 (POR 4.92),吸烟 (POR 3.24) 和低收入 (POR 2.34).
结论:
- 确定的风险因素为印尼制定有效的结核病预防策略提供了基础.
- 这些发现可以为旨在减少成年人结核病发病率的公共卫生政策提供信息.
- 针对家庭接触,营养和生活条件等可修改因素对结核病控制至关重要.
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