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分析和工程mollemycin A的生物合成途径,以提高其生产

Shixue Jin1, Huixue Chen1, Jun Zhang2

  • 1School of Pharmacy, Fudan University, Shanghai, 201203, China.

Synthetic and systems biotechnology
|April 12, 2024
PubMed
概括

抗疟疾化合物莫莱米辛A (MOMA) 的生物合成基因集群已被确定. 通过中介优化,产量增加了44%,使用协同突变菌株进一步增加了2.6倍.

关键词:
亚齐诺三是一种生物合成工程 生物合成工程生物合成途径 生物合成途径基因集群是一种基因集群.莫莱米辛A 是一种药物.提高生产能力 提高生产能力

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