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Updated: Jun 28, 2025

Induction of Paralysis and Visual System Injury in Mice by T Cells Specific for Neuromyelitis Optica Autoantigen Aquaporin-4
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在抗原呈现细胞中禁止素表达:在中枢神经系统中诱导触发IgG4相关疾病的含义

Hinda Najem1,2, Victor A Arrieta1,2, Joseph Duffy1,2

  • 1Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.

Annals of case reports
|April 12, 2024
PubMed
概括

与免疫球蛋白G4相关的疾病 (IgG4-RD) 涉及中枢神经系统中免疫细胞的激活. 禁忌素可能会触发这种罕见的自身免疫性疾病,突出显示新的研究途径.

关键词:
抗原呈现方式与IgG4相关的疾病免疫活性激活 免疫活性激活髓状细胞 髓状细胞血细胞 血细胞禁止使用这种药物.T 细胞 T 细胞

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Antibody Binding Specificity for Kappa (Vκ) Light Chain-containing Human (IgM) Antibodies: Polysialic Acid (PSA) Attached to NCAM as a Case Study11:10

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T Cell Types and Functions01:24

T Cell Types and Functions

When T cells with CD4 markers are activated, they give rise to two types of effector cells: helper T cells and regulatory T cells. Meanwhile, T cells with CD8 markers differentiate into effector cytotoxic T cells. The differentiation of CD4 T cells into helper T cell subsets, such as Th1, Th2, and Th17 cells, is dependent on the antigen type, antigen-presenting cell, and regulatory cytokines.
Th1 cells stimulate dendritic cells to express necessary co-stimulatory molecules on their surfaces for...
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