在儿童中出现的COVID-19和喘
James P Senter1, Laura K Aisenberg1, Jesse W Dudley2
1Departments of Pediatrics.
Pediatrics
|April 12, 2024
概括
严重急性呼吸道综合征冠状病毒2 (SARS-CoV-2) 感染并没有增加儿童新喘诊断的风险. 这项研究证实了已知的儿科喘风险因素,为有SARS-CoV-2病史的儿童提供了护理信息.
科学领域:
- 儿童呼吸系统健康问题
- 传染病流行病学 传染病流行病学
- 喘研究的研究
背景情况:
- 呼吸道病毒感染是已知的儿童喘触发因素.
- 严重急性呼吸系统综合征冠状病毒2 (SARS-CoV-2) 可以导致严重的呼吸系统疾病.
- 需要对SARS-CoV-2对新的儿科喘诊断的影响进行调查.
研究的目的:
- 为了确定SARS-CoV-2感染是否影响儿童新发喘的风险.
- 分析SARS-CoV-2阳性和发生喘诊断之间的关联.
- 为了确定患有或没有接触SARS-CoV-2的儿童喘发病的危险因素.
主要方法:
- 对1至16岁儿童进行回顾性队列研究.
- 对SARS-CoV-2的聚合酶链反应 (PCR) 测试结果的分析.
- 多变量考克斯回归模型根据人口统计,社会经济因素和亚托邦条件进行调整.
主要成果:
- SARS-CoV-2 PCR阳性与新的喘诊断没有显著的关联 (HR: 0.96,P = .79).
- 黑人种族,食物过敏和过敏性鼻炎是新的喘诊断的重要危险因素.
- 在5岁以下的儿童中,早产和BMI增加了喘风险.
结论:
- 在研究期间,SARS-CoV-2感染与儿童的新喘诊断无关.
- 确定的儿童喘风险因素得到证实.
- 结果提供了对SARS-CoV-2感染后儿童的预后和护理的见解.
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