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强大的黑激素受体配体的结合和解结合:机械模拟和实验证据

Annalida Bedini1, Gian Marco Elisi2, Fabiola Fanini1

  • 1Dipartimento di Scienze Biomolecolari, Università degli Studi di Urbino Carlo Bo, Urbino, Italy.

Journal of pineal research
|April 12, 2024
PubMed
概括

精确的黑激素受体结合亲和度测量需要长时间的潜伏时间,由于缓慢的连接体解离,特别是MT2亚型. 然而,较短的潜伏时间仍然产生可靠的结构-活性关系,反映结合位点相互作用.

关键词:
2 - - 甲氨酸二.在UCM101414中使用.结合动力学 结合动力学免费能源模拟的模拟.黑色素受体的受体是什么立体选择性的立体选择性.没有约束力的

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