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Updated: Jun 28, 2025

Myeloid Innate Signaling Pathway Regulation by MALT1 Paracaspase Activity
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整体蛋白αvβ3限制了血细胞状细胞的细胞因子产生,并限制了TLR驱动的自身免疫力

Alina K Lorant1,2, Anna E Yoshida1, Emily A Gilbertson1

  • 1Benaroya Research Institute at Virginia Mason, Seattle, WA.

Journal of immunology (Baltimore, Md. : 1950)
|April 12, 2024
PubMed
概括

整体素αvβ3调节了在血细胞状树突细胞 (pDCs) 中的托尔类受体 (TLR) 信号传递. 在pDC中删除αvβ3可增强IFN-I的产生和小鼠的狼类疾病.

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